Thorne Glycine
Glycine is one of the most abundant amino acids in the human body — and one of the most underappreciated in sports nutrition. It acts as a primary inhibitory neurotransmitter in the brainstem and spinal cord, it's a direct precursor to creatine synthesis, it contributes to glutathione production and liver detoxification, and it's a foundational building block of collagen.
For endurance athletes carrying the accumulated stress of high training volume, glycine quietly addresses multiple recovery demands at once. Thorne Glycine delivers a clean, flexible dose of one of the body's most functionally versatile amino acids.
CNS Calm and Sleep Quality – Glycine is a primary inhibitory neurotransmitter in the brainstem and spinal cord, where it modulates motor activity and stress signaling. Taken before bed, it lowers core body temperature — a key trigger for sleep onset — and clinical research shows it improves sleep quality, reduces daytime fatigue, and supports memory retrieval in sleep-deprived individuals. Calming support without sedation or dependency.
Creatine Precursor — Supporting Your Body's Own Production – Creatine is synthesized from three amino acids: arginine, methionine, and glycine. Adequate glycine availability supports the natural creatine production pathway — particularly relevant for plant-based athletes whose dietary glycine from animal connective tissue is limited.
Connective Tissue Foundation – Glycine is the most abundant amino acid in collagen, constituting roughly one-third of its structure. For endurance athletes accumulating repetitive mechanical stress on tendons and joints over long training blocks, glycine provides the foundational substrate for collagen synthesis and connective tissue maintenance.
Glutathione and Liver Detox Support – Glycine participates directly in phase II liver detoxification and contributes to glutathione synthesis. At high training volumes, metabolic waste production accelerates — glycine helps keep the body's clearance pathways running at pace.
How to Use Thorne Glycine
Daily Dose: Take 2 capsules three times daily with food, or as recommended by your healthcare practitioner. At 1g per 2-capsule serving, this delivers up to 3g glycine daily — consistent with the doses used in sleep quality research.
For Sleep Support: Take one full serving (2 capsules) 30–60 minutes before bed. Glycine's core body temperature-lowering effect is most relevant in the pre-sleep window.
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Description
Glycine is one of the most abundant amino acids in the human body — and one of the most underappreciated in sports nutrition. It acts as a primary inhibitory neurotransmitter in the brainstem and spinal cord, it's a direct precursor to creatine synthesis, it contributes to glutathione production and liver detoxification, and it's a foundational building block of collagen.
For endurance athletes carrying the accumulated stress of high training volume, glycine quietly addresses multiple recovery demands at once. Thorne Glycine delivers a clean, flexible dose of one of the body's most functionally versatile amino acids.
CNS Calm and Sleep Quality – Glycine is a primary inhibitory neurotransmitter in the brainstem and spinal cord, where it modulates motor activity and stress signaling. Taken before bed, it lowers core body temperature — a key trigger for sleep onset — and clinical research shows it improves sleep quality, reduces daytime fatigue, and supports memory retrieval in sleep-deprived individuals. Calming support without sedation or dependency.
Creatine Precursor — Supporting Your Body's Own Production – Creatine is synthesized from three amino acids: arginine, methionine, and glycine. Adequate glycine availability supports the natural creatine production pathway — particularly relevant for plant-based athletes whose dietary glycine from animal connective tissue is limited.
Connective Tissue Foundation – Glycine is the most abundant amino acid in collagen, constituting roughly one-third of its structure. For endurance athletes accumulating repetitive mechanical stress on tendons and joints over long training blocks, glycine provides the foundational substrate for collagen synthesis and connective tissue maintenance.
Glutathione and Liver Detox Support – Glycine participates directly in phase II liver detoxification and contributes to glutathione synthesis. At high training volumes, metabolic waste production accelerates — glycine helps keep the body's clearance pathways running at pace.
How to Use Thorne Glycine
Daily Dose: Take 2 capsules three times daily with food, or as recommended by your healthcare practitioner. At 1g per 2-capsule serving, this delivers up to 3g glycine daily — consistent with the doses used in sleep quality research.
For Sleep Support: Take one full serving (2 capsules) 30–60 minutes before bed. Glycine's core body temperature-lowering effect is most relevant in the pre-sleep window.
